Studies suggest that women who have undergone weight loss surgery need to eat less fat after surgery in order to fully enjoy the benefits of surgery and protect liver function.The study is published before printing American Journal of Physiology-Endocrinology and Metabolism..
Over 42% of adults living in the United States are considered obese and are at increased risk of developing chronic health conditions such as type 2 diabetes. Heart disease Or cancer. According to the American Society for Metabolic and Bariatric Surgery, an estimated 256,000 people in the United States Weight loss 2019 (weight loss) surgery. Eighty percent of these cases are women.Benefits of Weight loss surgery-In addition to weight loss-Improved glucose tolerance test Cholesterol level, And overall heart health is improved. However, studies have shown that men and women do not respond equally to weight loss interventions. “There are signs of that [biological] Gender affects the degree of weight loss and improvement of comorbidities, “writes a new mouse study researcher.
The researchers studied a mouse model of vertical sleeve gastrectomy. Weight loss surgery The stomach has been reduced to about 15% of its original size. After treatment, some mice maintained a high-fat diet given prior to surgery, and others were fed a low-calorie diet. The researchers found that both male and female mice had better glucose tolerance and lost weight and body fat after surgery, even if they continued on a high-fat diet. However, men had a greater reduction in liver fat storage (liver triglycerides) than women. Male mice showed improvement in hepatic triglycerides regardless of diet, but only females on a low-calorie diet showed a significant improvement. According to the Fatty Liver Foundation, high levels of liver triglycerides are markers of fatty liver disease, affecting up to 100 million people in the United States. Fatty liver disease can cause liver cancer and liver failure in some cases.
“These data show women [high-fat diet] In light of the gender differences associated with weight loss surgery, the researchers “emphasize the importance of considering the additive effects of diet on surgical outcomes,” explained Dr. Darlene Sandval. .D at the University of Colorado Anschutz Medical Campus. , And the author of the corresponding study.
“Diet-dependent gender differences in response to vertical sleeve gastrectomy” before printing American Journal of Physiology-Endocrinology and Metabolism..
Chelsea R Hutch et al, Diet-dependent gender differences in response to vertical sleeve gastrectomy, American Journal of Physiology-Endocrinology and Metabolism (2021). DOI: 10.1152 / ajpendo.00060.2021
American Physiology Society
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A low-fat diet that is key to female liver health after weight loss surgery
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