A new system invented to prevent cardiovascular disease non-invasively

Zhao Weiwei, Hefei Institute of Physical Sciences, Chinese Academy of Sciences

Credits: Hefei Institutes of Physical Science, Chinese Academy of Sciences

Cardiovascular disease (CVD) is the leading cause of death in the world. Lipid monitoring in patients with coronary heart disease (CHD) is important to reduce the incidence of cardiovascular events. The traditional indicator, low-density lipoprotein cholesterol (LDL-C), tends to be false positive under certain conditions, but invasive routine blood lipid detection fluctuates with diet, exercise, and body weight. increase.

Therefore, a method that can be used in the long term Lipids Management is urgently needed.

New detection system featuring rapid and non-invasive detection of skin cholesterolWas successfully developed by a joint team of the Hefei Institute of Materials Science, the Chinese Academy of Sciences, and the University of Science and Technology of China, which can be used for long-term lipid management in CVD.

Professor WANG Yikun, who led the team, said, “Just put your hand and the system will give you cholesterol data. Cholesterol is one of several types of fats that play an important role in the body. We can track your fat in this easy way. “

Cholesterol in the skin does not fluctuate much in a short period of time.Their invention is now Clinical application, Cholesterol content of the skin, which is closely related to CVD of atherosclerosis, can be evaluated.

The detection system includes detection reagents and detection equipment. This reagent, which is associated with fluorescent groups, can specifically bind to cholesterol in the skin. The amount of binding reagent on the skin surface is positively correlated with the cholesterol content. After combining with skin cholesterol, the test site can be irradiated with excitation light of a specific wavelength to invert the fluorescence spectrum into information on skin cholesterol content. In this way, skin cholesterol is easily obtained.

This non-invasive system has the potential to be used for long-term monitoring of blood lipid levels in CVD, providing innovative detection methods for drug evaluation and blood lipid management in patients with cardiovascular disease.

The research results are Biomedical Engineering Online When Health and illness lipids..

Studies suggest “residual cholesterol” as an independent risk of heart attack and stroke

For more information:
Jiacheng Lai et al, Non-Invasive Skin Cholesterol Test: A Potential Substitute for LDL-C and apoB Serum Measurements, Health and illness lipids (2021). DOI: 10.1186 / s12944-021-01571-0

Provided by Hefei Physics Research Institute, Chinese Academy of Sciences

Quote: A new system invented to prevent cardiovascular disease, non-invasive (November 29, 2021) November 29, 2021 Obtained from non-filtrationly.html

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A new system invented to prevent cardiovascular disease non-invasively

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