Long-term exposure to high levels of air pollutants, especially particulate matter (PM2.5), is critical to the outcome of people hospitalized with COVID-19, according to a large multicenter observational study published in Europe. It seems to have an impact. The Clinical Microbiology and Infectious Diseases Conference (ECCMID) held online this year.
Researchers have found that the greater the exposure, the greater the risk. For each slight increase in long-term exposure to PM2.5 (ug / m³), the chances of using a ventilator more than tripled and the chances of staying in the ICU doubled.
“Our study draws attention to systematic inequality that may have made a big difference in the results of COVID-19 along race and ethnicity,” said Henry Ford Hospital in Detroit, USA. Dr. Anitashalal said. “Color communities are more likely to be located closer together Industrial pollution, And working in a business that exposes them Air pollution“.
According to the American Lung Association, Detroit is the 12th most polluted city in the United States, measured in fine particles throughout the year. pollution (PM2.5). Air pollution, including potentially harmful pollutants such as PM2.5 and toxic gases emitted from industry, homes and vehicles, can increase respiratory inflammation and oxidative stress and exacerbate existing lung disease. There is sex. Air pollution is associated with adverse health effects, including an increased risk of death from respiratory viruses such as influenza.
To investigate the association between air pollution and the severity of COVID-19 results, researchers were admitted to four large hospitals within the Henry Ford Health System between March 12 and April 24, 2020. We retrospectively analyzed data from 2,038 adults with COVID-19. Until May 27, 2020.
Researchers have data on where participants lived, and the US Environmental Protection Agency, PM2.5, ozone, and Lead paint (Percentage of houses built before 1960). They have COVID-19 results and PM2.5, ozone, lead paint, traffic, Hazardous waste, And wastewater discharge.
They found that men, blacks, obese patients, or patients with more severe long-term health were much more likely to be admitted to the ICU with a ventilator. The same was true for patients living in areas with high levels of PM2.5 and lead paint.
Even after considering potentially influential factors, including age, BMI, and underlying health status, the analysis shows that men are obese and have a more serious long-term health status after admission. It was found to be a good predictor of mortality. Similarly, higher PM2.5 was an independent predictor of ventilator and ICU stay, but was not at increased risk of dying from COVID-19.
“The important point is that living in a more polluted area is an independent risk factor for the severity of COVID-19 disease,” says Dr. Shallal. “It is not clear how air pollutants contribute to more serious illnesses, but long-term exposure to air pollution can damage the immune system, leading to both increased susceptibility to the virus and more serious viral infections. It is possible. Fine particles in air pollution can also act as carriers of the virus and increase its spread. Minimize the impact of COVID-19 in the most vulnerable areas of the highly industrialized community. Urgent further research is needed to guide policy and environmental protection. Residents. “
The authors point out that their study was observational and could not determine the cause. They adjusted for some influential factors, but added that other factors that were not completely controllable, such as the severity of the disease at the time of presentation, could contribute to the observed results.
Courtesy of the European Society of Clinical Microbiology and Infectious Diseases
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Air pollution contributes to the severity of COVID-19, suggesting studies in one of the most polluted cities in the United States
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