Buprenorphine misuse decreased in US adults with opioid use disorders between 2015 and 2019

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In 2019, nearly three-quarters of US adults who reported buprenorphine use had not misused the drug in the last 12 months, according to data from a nationally representative survey. In addition, misuse of buprenorphine in people with opioid use disorders was on a downward trend between 2015 and 2019, despite an increase in the number of people receiving buprenorphine treatment.Study published today JAMA network openWas conducted by the National Institute on Drug Abuse (NIDA), which is part of the National Institute of Health, and the Centers for Disease Control and Prevention.

Buprenorphine is FDA approved dosage treat Opioid To use disabilities and relieve severe pain.Buprenorphine, used to treat opioid use disorders, works by partial activation Opioid receptor Helps reduce opioid cravings, withdrawal, and overall use of other opioids in the brain.

By 2020, more than 93,000 people will die from drug overdose, 75% of which are opioid-related. However, in 2019, less than 18% of people with opioid use disorders over the past year will take drugs to treat their addiction, partly because of the stigma and barriers to access to these drugs. received.To prescribe buprenorphine for the treatment of opioid use disorders, clinicians Certified opioid treatment program, Or submit a notice of intent to the federal government and there is a limit to the number of patients that can be treated at one time. Very few clinicians are eligible to treat opioid use disorders with buprenorphine, and even fewer clinicians prescribe medications.

“Quality medical practice requires the provision of safe and effective treatments for health conditions, including: Substance Use Disorder.. This includes providing life-saving medications to people suffering from opioid use disorders, “said NIDA Director Nora D. Volkow, MD. Stigma and prejudice remaining in addicts and the drugs used to treat them. ”

Released by the US Department of Health and Human Services in April 2021 Updated buprenorphine clinical practice guidelines Expand access to treatment for opioid use disorders. However, barriers to the use of this treatment remain, including provider concerns about managing patients with opioid use disorders, lack of adequate reimbursement, and concerns about the risk of diversion. Abuse, And overdose. Misuse is defined as a patient taking medication in a manner not recommended by a doctor, including taking other people’s medication. Prescription drugs, Or take your prescription in large quantities, more often, or for longer than instructed.

To better understand the use and misuse of buprenorphine, researchers analyzed data on the use and misuse of prescription opioids containing buprenorphine from the 2015-2019 National Survey on Drug Use and Health (NSDUH). NSDUH is conducted annually by the Substance Abuse and Mental Health Services Department. It provides nationally representative data on prescription opioid use, misuse, opioid use disorders, and recent misuse motives in US private and uninstitutionalized populations.

Researchers found that nearly three-quarters of US adults who reported buprenorphine use in 2019 did not misuse buprenorphine in the last 12 months. Overall, an estimated 1.7 million people reported the use of prescribed buprenorphine over the past year, while 700,000 reported substance abuse. In addition, despite the recent increase in the number of patients receiving buprenorphine treatment, the proportion of people with opioid use disorders who misused buprenorphine tended to decline during the study period.

Importantly, for adults with opioid use disorders, the most common motivation for recent buprenorphine misuse is “because of being obsessed with opioids” (27.3%), with people craving for self-treatment. It indicates that you may be taking buprenorphine without a withdrawal prescription, symptoms associated with opioid use disorder, and “to relieve physical distress” (20.5%). In addition, adults taking buprenorphine were less likely to misuse buprenorphine than those who were not treated with drugs. Together, these findings highlight the urgent need to increase access to buprenorphine treatment, as receiving treatment may help reduce misuse of buprenorphine. In addition, strategies need to be developed to continue to monitor and reduce buprenorphine misuse.

The study also found that people who were not treated with drugs and those who lived in rural areas were more likely to misuse the drug. However, other factors such as racial / ethnic minority and living in poverty did not affect the misuse of buprenorphine.The authors of the study suggested both access and quality to address the current opioid crisis. Buprenorphine treatment People with opioid use disorders need improvement.

“Three-quarters of adults are taking Buprenorphine “Don’t misuse this drug. Many people with opioid use disorders are seeking help and treating their illness as clinicians,” said Wilson Compton, MD, Deputy Director of NIDA and Senior Author of the Study. This study also emphasizes the urgency of addressing racial and ethnic, health insurance, economic and geographical disparities in access to treatment. Opioid use disorder You have access to this life-saving drug. ”

Long-term medication may improve treatment satisfaction with opioid use disorders

For more information:
B Han, CM Jones, EB Einstein, WM Compton. Trends and characteristics of buprenorphine misuse in adults in the United States. JAMA network open.. DOI: 10.1001 / jamanetworkopen.2021.29409 (2021)

Quote: Buprenorphine misuse decreased in US adults with opioid use disorder between 2015 and 2019 (October 15, 2021). html

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Buprenorphine misuse decreased in US adults with opioid use disorders between 2015 and 2019

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