An international team of medical scientists published a perspective article in the journal Nature Immunology, Outlines ongoing research on why some people are resistant to SARS-CoV-2 infection. Their treatise states that little is currently known about why some individuals are immune to COVID-19, but stronger efforts to discover new ones to treat or prevent the disease. It suggests that it may lead to a method.
The authors state that the pandemic helped remind the global community of the remarkable variability of viral responses. Some are asymptomatic and others get sick and die. They also note the obvious differences that researchers have observed. For example, if one member of the family is uninfected and everyone around them is ill. Or someone who works in a high-risk environment but does not get sick.
The authors also note that, despite clues, no one really knows at this time why there are such fluctuations in response to SARS-CoV-2 infection. For example, there are some reports that people with ABO blood group suffer less when infected. And there have been other studies suggesting that certain proteins produced by the body are more or less active when faced with the SARS-CoV-2 virus. It has been shown that the virus requires proteins with receptors such as ACE2 and TMEM41B. If people lack receptors, the virus cannot replicate.
The authors Volatility In response to SARS-CoV-2 infection. Such studies include subjects who believe they should be infected with the disease. In particular, such efforts will require the active recruitment of members of households in which one remains uninfected. They also state that the first steps in such research are already underway and that 400 volunteers who meet the required criteria have already signed on. The authors conclude by noting that the pandemic nature suggests SARS-CoV-2. virus It won’t go away soon. Therefore, it would be beneficial if the scientific community could fully understand why people react so differently when exposed to it.
Evangelos Andreakos, a global effort to analyze the human genetic basis for resistance to SARS-CoV-2 infection, Nature immunology (2021). DOI: 10.1038 / s41590-021-01030-z
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Global efforts to understand why some people are resistant to SARS-CoV-2 infection
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