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Quality, not quantity of cardiovascular fat, can interfere with later memory

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Deterioration of postmenopausal cardiovascular profiles can contribute to the fact that women are disproportionately affected by dementia. A new study identified a link between cardiovascular fat mass and radiation density and cognitive function, as well as racial differences in this link. The findings will be presented at the North American Menopause Association (NAMS) Annual Meeting in Washington, DC, September 22-25, 2021.

Cardiovascular fat deposits found to be higher in postmenopausal women compared to premenopausal women Cardiovascular disease.. It is also thought to affect cognitive function via neuropathological pathways by altering the secretion of inflammatory cytokines and adipokines. The quality of cardiovascular fat is characterized by its radiation density.

In this new study, researchers evaluated the association between cardiovascular fat mass and radiation density and future cognitive abilities of middle-aged women. Race difference At these associations. Blacks paradoxically have less cardiovascular fat, Heart disease The prevalence of Alzheimer’s disease is higher than that of Caucasians.

The study, based on SWAN (Study of Women’s Health Across the Nation) data, involved nearly 500 women, of whom 30.6% were postmenopausal and 35.9% were black. Research results suggest that higher radiation densities in perivascular adipose tissue (PVAT) are significantly associated with poor working memory performance. Researchers also identified a significant interaction between PVAT radiation density and race, and higher baseline PVAT radiation density in middle age resulted in lower future performance in episodic memory of blacks rather than white women. I paid attention to.Reported relevance includes the amount of PVAT depot and Waist circumference And other known confounding factors.

“Our study suggests that quality, not quantity, of perivascular adipose tissue in middle age may serve as a new biomarker for cognitive status in later women. Further research is needed to understand the underlying mechanisms of the association. ”Samar R, Pittsburgh University. Dr. El Khoudary states that he is the senior author of this study.

“Such research is valuable to support. Health provider We will identify who may be the most vulnerable and allow early intervention to slow the progression of the disease, “said Dr. Stephanie Faubion, Health Director of NAMS.


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Quote: Quality, not quantity of cardiovascular fat, can interfere with memory in later years (September 22, 2021). Obtained from https: //medicalxpress.com/news/2021-09-quality-quantity-cardiovascular-fat- on September 22, 2021 memory.html

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Quality, not quantity of cardiovascular fat, can interfere with later memory

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