Rapid decrease in amputation due to type 1 diabetes

Graphical abstraction. Credit: DOI: 10.1007 / s00125-021-05550-z

Amputation of type 1 diabetes has become relatively uncommon in Sweden. According to a study by the University of Gothenburg, this rate has fallen by more than 40% in about 20 years.

Results published in the journal Diabetes mellitus, Based on registry data of 46,088 people of type 1 Diabetes mellitus From 1998 to 2019. This study included linking data from the Swedish National Diabetes Register, the National Patient Register, and several other Swedish National Registers.

Researchers studied how the incidence of amputation changes over time and also investigated the risk factors for amputation in patients with type 1 diabetes.

The average age of patients covered by the data when included in the study was 32 years. At that time, none of them had been amputated. 55% were men and 45% were women.

Better trend reversal

Initially, between 1998 and 2001, the probability of disconnection was 2.84 per 1,000 people on an annual basis. In the last few years of the survey, 2017-2019, the corresponding numbers were 1.64 / 1,000. Therefore, the percentage of people who get amputated each year has decreased by 42 percent.

The lead author of this study is Sara Hallström, a PhD student in molecular and clinical medicine at the Sahlgrenska Academy in Gothenburg University and a specialist in internal medicine at the Sahlgrenska University Hospital.

“The trend reversed between 2014 and 2016, and a few years earlier there was a clear long-term decrease in blood glucose and improved renal function. These are risk factors demonstrated in the study. It’s a major cause of amputation in people with type 1 diabetes, “says Hallström.

Other risk factors identified were older age, male gender, cardiovascular disease, smoking, and hypertension.

More care, less pain

In the researchers’ view, the improvement in prognosis is probably due to recent developments in diabetes treatment.Intensive care Risk factor For example, it can be affected by continuous blood glucose measurements and the use of advanced insulin pumps. An interdisciplinary diabetic foot team has also been introduced.

The team assists the patient Wounds on the foot They are not easily cured due to vascular changes and sensory disorders that diabetes can cause. Ultimately, unhealing wounds may require amputation of the leg, and in more severe cases, amputation of the lower extremities and thighs.

“Reducing amputation rates in diabetics is important. Disconnect It’s a procedure that causes great pain and disability for those who have to experience it, “says Hallström.

Amputation of toes and feet increased in minority, diabetic rural population

For more information:
Sara Hallströmetal, Risk Factors and Incidence of Amputation in Patients with Type 1 Diabetes: An Observation Cohort Study of 46,088 Patients from the Swedish National Diabetes Registry, Diabetes mellitus (2021). DOI: 10.1007 / s00125-021-05550-z

Quote: A sharp decrease in amputation due to type 1 diabetes (September 8, 2021) from https: // September 2021 Obtained on the 8th

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Rapid decrease in amputation due to type 1 diabetes

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