Smart wound dressing provides suture-free closure of surgical incisions

Credit: AIXabay / CC0 public domain

“Suture? It’s virtually medieval!”

Mocking sutures as obsolete is a staple of science fiction novels. After all, this technique has been in use for at least 5,000 years. Certainly medicine must have progressed since ancient Egypt. Professor Hossum Haiku of Technion’s Wolfson Department of Chemical Engineering has finally made science fiction a reality.His lab has succeeded in creating a smart, suture-free dressing that stitches and avoids wounds. infection, And report the condition of the wound directly to the doctor’s computer.Their research is Advanced material.

Current surgical procedures are performed by the surgeon human bodyDo what you need to do and sew the wound together. This is an invasive procedure that damages the surrounding healthy tissue. Some sutures either deteriorate or should deteriorate on their own as the wound heals. Others need to be removed manually. The bandage is then applied to the wound so that medical personnel can remove the bandage and monitor the wound to observe signs of infection such as swelling, redness, and fever. This procedure is painful for the patient and hinders healing, but it is unavoidable. With these methods, infections are often detected late because it takes time for visible signs to appear and it takes time for tests to be performed to confirm them. In developed countries where good hygiene is available, about 20% of patients develop postoperative infections, requiring additional treatment and longer time to recovery. The numbers and results are much worse in developing countries.

How do you work with Professor Haiku’s new dressing?

Before starting the procedure, a dressing developed by Professor Haick’s laboratory (much like a smart band-aid) is applied to the site of the planned incision. Then the incision is made through it. After surgery, the ends of the wound come together and within 3 seconds the bandages bind to each other, leaving the wound closed, similar to a suture. From then on, the dressing continuously monitors the wound and Healing processCheck for signs of infection, such as changes in temperature, pH, and blood sugar, and report to your healthcare professional’s smartphone or other device. The bandage itself also releases antibiotics into the wound area to prevent infection.

“I was watching a movie about future robotics with my kids late one night, and I wondered what would happen if we could really make a self-healing sensor,” said Professor Haiku. Told.

Most people throw away ideas inspired by late-night movies. He is not Professor Haiku, who was researching and planning the day after the moment of Eureka. The first publication on self-healing sensors was published in 2015. At that time, the sensor took almost 24 hours to repair itself. By 2020, the sensor had healed in less than a minute, had multiple uses, but was not yet biocompatible. In other words, it could not be used in contact with skin or blood. The next step was to create a polymer that was both biocompatible and self-healing, and was accomplished by postdoctoral fellow Dr. Ning Tang.

The new polymer is structured like a molecular zipper made of sulfur and nitrogen. The surgeon’s scalpel opens it. Then press together to close and hold firmly. The integrated carbon nanotubes provide conductivity and sensor array integration. In the experiment scratch Smart and closed dressing It healed as quickly as closed with sutures, showing a reduced infection rate.

“This is a new approach to wound healing,” said Professor Haick. “We are introducing smart interconnect devices, an advancement of the Fourth Industrial Revolution, into the routine treatment of patients.”

Professor Haick is the Head of the Nanomaterials Based Devices Institute (LNBD) and Dean of the Undergraduate Department at Technion. Dr. Ning Tang is a postdoctoral fellow in Professor Haick’s lab and conducted this research as part of his fellowship. He is currently appointed as an associate professor at Shanghai Jiao Tong University.

Diamond-studded silk wound dressing detects infection and improves healing

For more information:
Ning Tang et al, a highly efficient self-healing multifunctional dressing with antibacterial activity for non-sutured wound closure and infected wound monitoring, Advanced material (2021). DOI: 10.1002 / adma.202106842

Quote: Smart Wound Dressing is a surgical incision obtained on November 29, 2021 from https: // (2021). Offers closure without sutures (November 29)

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Smart wound dressing provides suture-free closure of surgical incisions

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