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Studies Link Diabetes Drugs to Glaucoma Prevention

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A popular class of diabetes medications called GLP-1R agonists (Trulicity and Rybelsus) may also prevent glaucoma in diabetics, according to a new study led by researchers at the Scheie Eye Institute at the University of Pennsylvania’s Perelman School of Medicine.Survey results published in British Journal of Offtalmology..

Researchers examined retrospective data from 1961 Diabetics We were new users of this class of drugs and matched with 4,371 unexposed control subjects.After an average of 150 days, 10 patients in the medicinal group were newly diagnosed Glaucoma Compared to 58 patients (1.3%) in the control group (0.5%). The findings suggest that GLP-1 receptor agonists may halve the risk of developing glaucoma in diabetics.

Survey results are supported According to Penn Medical Research from 2020, GLP-1R agonists have been found to reduce neuroinflammation and prevent retinal ganglion cell death in mice. This class of drugs has similar protective effects against Alzheimer’s disease and Parkinson’s disease in animal models. Clinical trials In progress to test the drug against Neurodegenerative diseases In humans.

Glaucoma affects 3 million Americans and is the second most common cause of blindness in the world. People with diabetes are twice as likely to develop eye conditions.

“It was very encouraging to see that popular diabetes medications can significantly reduce the risk of developing glaucoma. Our study is that these medications are further studied in this patient population. It suggests justifying, “Qi N. Cui, MD, Ph.D. Says. Brian Vanderbeek, MD and MPH, Associate Professor of Ophthalmology, University of Pennsylvania.


Types of glaucoma associated with increased risk of cognitive impairment


For more information:
Jacob Sterling et al, the use of glucagon-like peptide 1 receptor agonists is associated with a reduced risk of glaucoma. British Journal of Offtalmology (2021). DOI: 10.1136 / bjophthalmol-2021-319232

Quote: The study obtained a diabetes drug obtained on September 20, 2021 from https://medicalxpress.com/news/2021-09-links-diabetes-medications-glaucoma.html for glaucoma prevention (September 20, 2021). Link to day)

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Studies Link Diabetes Drugs to Glaucoma Prevention

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